Psychological Medicine



Original Article

Psychological risk factors of incidence of breast cancer: a prospective cohort study in Finland


A. R. ARO a1a2c1, H. J. DE KONING a2, M. SCHRECK a1, M. HENRIKSSON a3, A. ANTTILA a4 and E. PUKKALA a4
a1 Department of Epidemiology and Health Promotion, National Public Health Institute, Helsinki, Finland
a2 Department of Public Health, Erasmus MC and NIHES, Rotterdam, The Netherlands
a3 Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland
a4 Finnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland

Article author query
aro ar   [PubMed][Google Scholar] 
koning hj   [PubMed][Google Scholar] 
schreck m   [PubMed][Google Scholar] 
henriksson m   [PubMed][Google Scholar] 
anttila a   [PubMed][Google Scholar] 
pukkala e   [PubMed][Google Scholar] 

Abstract

Background. Belief that depression and other psychological factors predict breast cancer is common, but there have been few prospective epidemiological studies on this relationship.

Method. The relationship between depression, personality traits, illness attitudes, life events and health history, and breast cancer risk was studied in a prospective, 6–9 year follow-up of a cohort study of 10892 Finnish women of 48–50 years of age at the baseline. Cancer cases were obtained from the Cancer Registry of Finland. Multivariate logistic regression analysis was performed controlling for socioeconomic factors, family history of cancer, parity, and health behaviours.

Results. Breast cancer incidence in the cohort was 1·15 times the average in age group 50–59. There was no evidence of depression, trait anxiety, cynical distrust, or coping being significant predictors of breast cancer incidence.

Conclusion. In this cohort study with the 6–9 year follow-up, psychological factors such as depression, trait anxiety, cynical distrust, or coping did not increase breast cancer risk.


Correspondence:
c1 Department of Epidemiology and Health Promotion, National Public Health Institute, Mannerheimintie 166, FIN-00300 Helsinki, Finland. (Email: arja.aro@ktl.fi)


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