International Psychogeriatrics

Dementia associated with psychiatric disorders

John O'Brien a1c1
a1 Institute for Ageing and Health, University of Newcastle upon Tyne, U.K.

Article author query
o'brien j   [PubMed][Google Scholar] 


Functional psychiatric disorders are associated with a variety of cognitive deficits and, in some instances, severe cognitive impairment. This paper reviews the cognitive profile of patients with schizophrenia, depression, bipolar and anxiety disorders, as well as the longitudinal course and clinical outcome of the cognitive impairment associated with these conditions. The paper also discusses some of the mechanisms that may contribute to the expression of the cognitive deficits in these disorders and their potential relationship with common causes of dementia.

Key Words: schizophrenia; depression; bipolar disorder; anxiety disorder; neuropsychology; cognitive function; cognitive impairment.

c1 Correspondence should be addressed to: John O'Brien, Wolfson Research Centre, Institute for Ageing and Health, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne NE4 6BE, U.K. Phone: +44-0191-256–3323; Fax: +44-0191-219–5051. Email: j.t.o'