Open Peer Commentary Depue & Collins: Neurobiology of personality
Is depression a dysfunction in self-regulating the brain/behavior system for approach?
Timothy J. Strauman a1 a1 Department of Psychiatry, University of Wisconsin-Madison, Madison, WI 53719-1176
This commentary examines the implications of the Depue
& Collins model for the etiology and treatment of depression,
specifically, whether it can account for findings concerning
neurobiological, behavioral, and phenomenological facets of
depression. Drawing upon the construct of self-regulation,
I explore the fit of the model to current knowledge about depression,
conceptualized as a dysfunction within a hypothetical brain/behavior
system for maximizing positive outcomes.