|Behavioral and Brain Sciences (2004), 27:6:856-856 Cambridge University Press|
Copyright © 2005 Cambridge University Press
Schizophrenia is a disease of general connectivity more than a specifically “social brain” network
Dysfunctions of the neural circuits that implement social behavior are necessary but not a sufficient condition to develop schizophrenia. We propose that schizophrenia represents a disease of general connectivity that impairs not only the “social brain” networks, but also different neural circuits related with higher cognitive and perceptual functions. We discuss possible mechanisms and evolutionary considerations.