Open Peer Commentary Fitch & Denenberg: Sexual differentiation of the brain
More evidence for the role of estrogens in female differentiation of the brain
Klaus D. Döhler a1 a1 Haemopep Pharma GmbH, D-30625 Hannover, Germany
Abstract
Evidence accumulates that pre- and postnatally circulating
estrogens play an active role in the differentiation of the female
brain: the susceptible period for feminization of the brain seems to
extend far beyond the period during which masculinization of the
brain occurs. Thus, there is a need to reevaluate the widely accepted
“concept of basic femaleness” in sexual brain
differentiation.
