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Sexual differentiation of callosal size: Hormonal mechanisms and the choice of an animal model

Published online by Cambridge University Press:  01 June 1998

M. J. Baum
Affiliation:
Department of Biology, Boston University, Boston, MA 02215 baum@bio.bu.edu Program in Neuroscience, Harvard Medical School, Boston, MA 02115
S. A. Tobet
Affiliation:
Department of Biomedical Sciences, The Shriver Center, Waltham, MA 02254 stobet@shriver.org Program in Neuroscience, Harvard Medical School, Boston, MA 02115

Abstract

Studies of callosal sexual differentiation have concentrated on global measures of callosal size, using the rat as a model for studies of potential hormonal mechanisms. It is time to shift the study of callosal sexual differentiation to a more cellular level. Finally, there are potential problems with using the female rat as the primary model for understanding hormonal mechanisms during postnatal life.

Type
Open Peer Commentary
Copyright
© 1998 Cambridge University Press

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