International Psychogeriatrics

IPA Expert Consensus Conference “Vascular Burden of the Brain: New Therapeutic Directions”

Epidemiology of White-Matter Lesions

Lenore J. Launer a1
a1 Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, MD, US

Article author query
launer l   [PubMed][Google Scholar] 


White-matter lesions (WML) detected on MRI may reflect different pathologies, but, in older persons, are thought to be mainly of ischemic origin. WML increase in prevalence with age. Several cardiovascular risk factors and cognitive, emotional, and physical function consequences of WML have been identified. These are reviewed briefly in this report.

Key Words: Epidemiology; white-matter lesions; risk factors.