International Psychogeriatrics


IPA Expert Consensus Conference “Vascular Burden of the Brain: New Therapeutic Directions”
BACKGROUND AND CURRENT CONCEPTS OF ETIOPATHOGENESIS

Mixed Dementia: Alzheimer's and Cerebrovascular Disease


Kenneth Rockwood a1
a1 Dalhousie University, Halifax, Nova Scotia, Canada

Article author query
rockwood k   [PubMed][Google Scholar] 

Abstract

“Mixed dementia” is traditionally defined as Alzheimer's disease with cerebrovascular disease (CVD). Because the risks of both neurodegenerative dementias and cerebrovascular disease increase with age, the mixed dementias are likely the most common. In practice, patients with mixed dementia are diagnosed by one of two routes: Either they have evidence of a neurodegenerative dementia and CVD at the outset, or, they have a classical neurodegenerative presentation but are found to have ischemic lesions by neuroimaging. These facts have implications for the development of evidence-based diagnostic criteria.


Key Words: Mixed dementia; Alzheimer's disease; vascular dementia; diagnostic criteria.