Behavioral and Psychological Symptoms of Dementia (BPSD): A Clinical and Research Update Pharmacologic Approaches
Selective Serotonin Reuptake Inhibitors and Trazodone for Treatment of Depression, Psychosis, and Behavioral Symptoms in Patients With Dementia
David L. Sultzer a1a2 a1 Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles School of Medicine, Los Angeles, California, USA a2 Mental Health Services, VA Greater Los Angeles Healthcare System, Los Angeles, California, USA.
Depression, psychosis, agitation, and aggression are fundamental clinical aspects of Alzheimer's disease (AD) and other dementia syndromes. Although behavioral, environmental, and pharmacologic interventions often help ameliorate these symptoms, the efficacy of specific interventions is uncertain, and adverse effects of medications are common.
