International Psychogeriatrics

Clinical Practice and Service Development

Effect of Elective Surgery Under General Anesthesia on Mental Status Variables in Elderly Women and Men: 10-Month Follow-Up

Marion Zucker Goldstein a1a3, Barry Steven Fogel a4 and Bruce Leonard Young a2
a1 Department of Psychiatry and Internal Medicine, School of Medicine and Biomedical Sciences, New York, U.S.A.
a2 Department of Psychology, State University of New York at Buffalo, New York, U.S.A.
a3 Erie County Medical Center, Buffalo, New York, U.S.A.
a4 Center for Gerontology and Health Care Research, Brown University, Providence, Rhode Island, U.S.A.

Article author query
goldstein m   [PubMed][Google Scholar] 
fogel b   [PubMed][Google Scholar] 
young b   [PubMed][Google Scholar] 


Mental status changes were assessed and compared in 172 general surgical and orthopedic patients and 190 nonsurgical patients, all aged 55 and over, during a 10-month period. Assessments included a structured psychosocial questionnaire and standardized tests of cognition, affect, and function. The relationship of surgery, type of surgery, age, gender, and postoperative delirium to long-term postoperative decline was evaluated. Analyses of variance directly tested main effects pertaining to each of the five hypotheses and interactions of surgery with background variables. Hierarchical multiple regression analyses assessed the unique contributions of demographic and surgical variables to cognitive, affective, and functional change. None of the independent variables tested made a significant contribution to changes from baseline to long-term follow-up. The findings may be due to the physical and psychological health of this sample, and replication of this work in more impaired populations may be productive.