The Journal of Laryngology & Otology

Clinical Records

Adult cystic hygroma: successful use of OK-432 (Picibanil®)

S L Woolleya1 c1, D R K Smitha2 and S Quinea2

a1 Emergency Department, Bristol Royal Infirmary, University Hospital of Wales, Cardiff, Wales, UK

a2 Otolaryngology Department, University Hospital of Wales, Cardiff, Wales, UK


Objective: We report an adult case of cystic lymphangioma treated with OK-432 (Picibanil®).

Method: A case report and review of the literature concerning the use of OK-432 to treat cystic lymphangioma is presented.

Results: A 31-year-old woman developed a cystic lymphangioma four weeks post-partum. This was treated initially by aspiration, for diagnostic purposes. Investigation suggested that surgery would be challenging. A review of the literature demonstrated success with OK-432 in the treatment of this condition, although primarily in the paediatric population. This patient was successfully treated thus, and at the time of writing remained symptom free. A suggested management plan is outlined.

Conclusion: Treatment with OK-432 is useful in the management of cystic lymphangiomas in adults and should be considered as first line treatment.

(Accepted August 02 2007)

(Online publication April 23 2008)


Dr S L Woolley takes responsibility for the integrity of the content of the paper.

Competing interests: None declared