Journal of the International Neuropsychological Society



Longitudinal outcomes of very low birth weight: Neuropsychological findings


H. GERRY  TAYLOR  a1 c1 , NORI M.  MINICH  a1 , NANCY  KLEIN  a2 and MAUREEN  HACK  a1
a1 Department of Pediatrics, Case Western Reserve University and Rainbow Babies & Children's Hospital, University Hospitals of Cleveland, Cleveland, Ohio
a2 Department of Special Education, Cleveland State University, Cleveland, Ohio

Article author query
taylor hg   [PubMed][Google Scholar] 
minich nm   [PubMed][Google Scholar] 
klein n   [PubMed][Google Scholar] 
hack m   [PubMed][Google Scholar] 

Abstract

To investigate the effects of very low birth weight (VLBW, <1500 g) on the development of neuropsychological skills, we assessed 67 children with birth weight <750 g, 64 with birth weight 750–1499 g, and 67 term-born controls. Growth modeling of raw scores from mean ages 7–14 years revealed persistent VLBW sequelae. Even when adjusting for IQ, the <750 g group scored more poorly than the term-born group on measures of language processing, verbal list learning, and perceptual–motor and organizational abilities. This group also made slower age-related progress than the control group on tests of perceptual-motor and executive functions. Environmental factors moderated group differences in change on other cognitive measures. These results revealed further evidence for slower skill development in both VLBW groups relative to controls, as well as“catch-up” growth in the 750–1499 g group on some measures. The findings suggest age-related changes in the cognitive sequelae of VLBW that depend on the skill assessed, the degree of VLBW, and environmental factors. (JINS, 2004, 10, 149–163.)

(Received February 20 2003)
(Revised June 17 2003)
(Accepted June 17 2003)


Key Words: Very low birth weight; Neuropsychological sequelae; Developmental change.

Correspondence:
c1 Reprint requests to: H. Gerry Taylor, Ph.D., Department of Pediatrics, Rainbow Babies & Children's Hospital, 11100 Euclid Avenue, Cleveland, OH 44106-6038. E-mail: hgt2@po.cwru.edu