The Journal of Laryngology & Otology

Clinical Records

Gorlin's syndrome presenting with myolipoma of tongue base

L Barkera1, S Loa1 c1 and R Suddericka1

a1 Department of Otolaryngology, Royal Surrey County Hospital, Guildford, UK


Objective: We report the first case of tongue base myolipoma associated with Gorlin's syndrome.

Method: Case report and review of world literature.

Results: A 39-year-old man with known Gorlin's syndrome presented with progressive dysphagia. Subsequent magnetic resonance imaging scan and biopsy confirmed the rare diagnosis of myolipoma arising from the tongue base. In view of the benign nature of this mass, it was debulked rather than completely excised in order to preserve swallowing function.

Conclusion: To our knowledge, this is the first report of the coexistence of two rare conditions in an atypical fashion. This case appears to represent a new variant in the broad spectrum of features of Gorlin's syndrome.

(Accepted June 11 2007)

(Online publication October 02 2007)


c1 Address for correspondence: Dr Stephen Lo, Department of Otolaryngology, Royal Surrey County Hospital, Guildford GU2 7XX, UK. Fax: 01483 464108 E-mail:


Mr S Lo takes responsibility for the integrity of the content of the paper.

Competing interests: None declared