Biofilms



Rheology of biofilms formed from the dental plaque pathogen Streptococcus mutans


A. M. Vinogradov a1, M. Winston a1a2, C. J. Rupp a1a2 and P. Stoodley a3c1
a1 Department of Mechanical and Industrial Engineering, Montana State University–Bozeman, Bozeman, MT 59717, USA
a2 Center for Biofilm Engineering, Montana State University–Bozeman, Bozeman, MT 59717, USA
a3 Departments of Microbiology and Civil Engineering, Montana State University–Bozeman, Bozeman, MT 59717, USA

Article author query
vinogradov a   [PubMed][Google Scholar] 
winston m   [PubMed][Google Scholar] 
rupp c   [PubMed][Google Scholar] 
stoodley p   [PubMed][Google Scholar] 

Abstract

Here we describe an experimental study of the mechanical properties of bacterial biofilms formed from the early dental plaque colonizer Streptococcus mutans. The S. mutans biofilms demonstrated the behavior of rheological fluids, with properties similar to those of organic polymers and other biological fluids. The time-dependent response of the biofilms was modeled on the basis of principles of viscoelasticity theory. The static and dynamic responses were defined in terms of the creep compliance, storage and loss moduli, and viscosity. The creep compliance and stress relaxation functions of S. mutans biofilms were characterized using the Burger model. Implications for developing more effective mechanical removal strategies of dental plaque biofilms are discussed.


Correspondence:
c1 Corresponding author: Dr P. Stoodley, Departments of Microbiology and Civil Engineering, Montana State University–Bozeman, Bozeman MT 59717, USA T 1 406 994 7361, F 1 406 994 6098, E paul_s@erc.montana.edu