Epidemiology and Infection



Antibiotic resistance in Salmonella enterica serotypes Typhimurium, Enteritidis and Infantis from human infections, foodstuffs and farm animals in Italy


L. BUSANI a1c1, C. GRAZIANI a1, A. BATTISTI a2, A. FRANCO a2, A. RICCI a3, D. VIO a3, E. DIGIANNATALE a4, F. PATERLINI a5, M. D'INCAU a5, S. OWCZAREK a6, A. CAPRIOLI a1 and I. LUZZI a6
a1 Laboratorio di Medicina Veterinaria, Istituto Superiore di Sanità, Rome, Italy
a2 Istituto Zooprofilattico Sperimentale delle Regioni Lazio e Toscana, Rome, Italy
a3 Istituto Zooprofilattico Sperimentale delle Venezie, Legnano, Italy
a4 Istituto Zooprofilattico Sperimentale dell' Abruzzo e del Molise, Teramo, Italy
a5 Istituto Zooprofilattico Sperimentale della Lombardia ed Emilia Romagna, Brescia, Italy
a6 Laboratorio di Batteriologia e Micologia Medica, Istituto Superiore di Sanità, Rome, Italy

Article author query
busani l   [PubMed][Google Scholar] 
graziani c   [PubMed][Google Scholar] 
battisti a   [PubMed][Google Scholar] 
franco a   [PubMed][Google Scholar] 
ricci a   [PubMed][Google Scholar] 
vio d   [PubMed][Google Scholar] 
digiannatale e   [PubMed][Google Scholar] 
paterlini f   [PubMed][Google Scholar] 
d'incau m   [PubMed][Google Scholar] 
owczarek s   [PubMed][Google Scholar] 
caprioli a   [PubMed][Google Scholar] 
luzzi i   [PubMed][Google Scholar] 

Abstract

The antimicrobial susceptibility of isolates of Salmonella enterica serotypes Typhimurium, Enteritidis, and Infantis isolated from humans, foodstuffs and farm animals in Italy between 1999 and 2001 was examined. All the isolates were susceptible to cefotaxime and ciprofloxacin, but high rates of resistance were observed for several other drugs, especially for S. Typhimurium. The rates of resistance and multiresistance were generally higher among animal and food isolates than in human strains; conversely, no significant difference was observed between animal and food isolates. Among S. Typhimurium, multiresistance was more common in bovine, poultry and rabbit strains than in swine isolates, and was rare in strains from pigeon. Resistance to trimethoprim–sulphamethoxazole was mainly found in isolates of swine and human origin. This study confirms the role of livestock as a reservoir of drug-resistant Salmonella spp. and underlines the need for integrated surveillance systems of antibiotic resistance that consider isolates not only from human disease but also from the animal reservoirs and the food vehicles.

(Accepted November 24 2003)


Correspondence:
c1 Dr L. Busani, Istituto Superiore di Sanità, Laboratorio di Medicina Veterinaria, Viale Regina Elena, 299 I-00161 Rome, Italy.


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