Epidemiology and Infection



Present characteristics of symptomatic Entamoeba histolytica infection in the big cities of Japan


K. OHNISHI a1c1, Y. KATO a1, A. IMAMURA a2, M. FUKAYAMA a3, T. TSUNODA a4, Y. SAKAUE a5, M. SAKAMOTO a6 and H. SAGARA a6
a1 Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, Tokyo, Japan
a2 Department of Infectious Diseases, Tokyo Metropolitan Komagome General Hospital, Tokyo, Japan
a3 Department of Infectious Diseases, Tokyo Metropolitan Toshima General Hospital, Tokyo, Japan
a4 Department of Infectious Diseases, Tokyo Metropolitan Ebara General Hospital, Tokyo, Japan
a5 Infectious Disease Centre, Osaka City General Hospital, Osaka, Japan
a6 Department of Infectious Diseases, Yokohama Municipal Citizens' Hospital, Yokohama, Japan

Article author query
ohnishi k   [PubMed][Google Scholar] 
kato y   [PubMed][Google Scholar] 
imamura a   [PubMed][Google Scholar] 
fukayama m   [PubMed][Google Scholar] 
tsunoda t   [PubMed][Google Scholar] 
sakaue y   [PubMed][Google Scholar] 
sakamoto m   [PubMed][Google Scholar] 
sagara h   [PubMed][Google Scholar] 

Abstract

Medical records, for 2000 and 2001, of symptomatic amoebic patients who were treated at our hospitals in Tokyo, Yokohama and Osaka were studied retrospectively for the purpose of gathering epidemiological data on symptomatic Entamoeba histolytica infection. A total of 58 patients were treated. Fifty-five of them were male, and 96% of the male patients were Japanese. The mean age of patients was 44·9 years old, and 91% of patients contracted the disease in Japan. Fifty-six per cent of the male patients indicated that they were practising homosexuals, and 44% of the male patients denied these practices or left the question unanswered. The serum Treponema pallidum haemagglutination test was positive in 45% of the patients, and antibody to human immunodeficiency virus (HIV) was positive in 45%. Our study revealed that recent symptomatic E. histolytica infection almost exclusively afflicted middle-aged males in the big cities of Japan, that a majority of the patients were probably exposed to the causative organism during homosexual activity, and that an increasing number of patients will be co-infected with HIV.

(Accepted July 24 2003)


Correspondence:
c1 K. Ohnishi, Department of Infectious Diseases, Tokyo Metropolitan Bokutoh General Hospital, 4-23-15 Kohtohbashi, Sumida City, Tokyo 130-8575, Japan.


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