International Journal of Astrobiology

International Journal of Astrobiology (2003), 2:3:203-211 Cambridge University Press
Copyright © 2003 Cambridge University Press
doi:10.1017/S1473550403001551

Phylogeny of Opisthokonta and the evolution of multicellularity and complexity in Fungi and Metazoa


Mónica Medina a1a5c1p1, Allen G. Collins a2a3, John W. Taylor a4, James W. Valentine a3, Jere H. Lipps a3, Linda Amaral-Zettler a1 and Mitchell L. Sogin a1
a1 Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA 02543, USA
a2 ITZ, Ecology & Evolution, Tierärztliche Hochschule Hannover, Bünteweg 17d, 30559 Hannover, Germany
a3 Department of Integrative Biology and Museum of Paleontology, University of California, Berkeley, CA 94720, USA
a4 Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
a5 DOE Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA

Article author query
medina m   [PubMed][Google Scholar] 
collins a   [PubMed][Google Scholar] 
taylor j   [PubMed][Google Scholar] 
valentine j   [PubMed][Google Scholar] 
lipps j   [PubMed][Google Scholar] 
amaral-zettler l   [PubMed][Google Scholar] 
sogin m   [PubMed][Google Scholar] 

Abstract

While early eukaryotic life must have been unicellular, multicellular lifeforms evolved multiple times from protistan ancestors in diverse eukaryotic lineages. The origins of multicellularity are of special interest because they require evolutionary transitions towards increased levels of complexity. We have generated new sequence data from the nuclear large subunit ribosomal DNA gene (LSU rDNA) and the SSU rDNA gene of several unicellular opisthokont protists – a nucleariid amoeba (Nuclearia simplex) and four choanoflagellates (Codosiga gracilis, Choanoeca perplexa, Proterospongia choanojuncta and Stephanoeca diplocostata) to provide the basis for re-examining relationships among several unicellular lineages and their multicellular relatives (animals and fungi). Our data indicate that: (1) choanoflagellates are a monophyletic rather than a paraphyletic assemblage that independently gave rise to animals and fungi as suggested by some authors and (2) the nucleariid filose amoebae are the likely sister group to Fungi. We also review published information regarding the origin of multicellularity in the opisthokonts.

(Received April 1 2003)
(Accepted July 10 2003)


Key Words: Choanoflagellata; Fungi; Mesomycetozoea; Metazoa; multicellularity; Nuclearia; Opisthokonta.

Correspondence:
c1 Corresponding author.
p1 Present address: Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA. e-mail: m_medina@lbl.gov


null