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Covariance between direct and maternal genetic effects in mice, with a model of persistent environmental influences

Published online by Cambridge University Press:  14 April 2009

Bruce Riska ,
J. J. Rutledge  and
William R. Atchley
Bruce Riska
Affiliation:
Laboratory of GeneticsUniversity of Wisconsin, Madison, Wisconsin 53706, U.S.A.
J. J. Rutledge
Affiliation:
Laboratory of GeneticsUniversity of Wisconsin, Madison, Wisconsin 53706, U.S.A. Department of Meat and Animal ScienceUniversity of Wisconsin, Madison, Wisconsin 53706, U.S.A.
William R. Atchley
Affiliation:
Laboratory of GeneticsUniversity of Wisconsin, Madison, Wisconsin 53706, U.S.A. Department of Meat and Animal ScienceUniversity of Wisconsin, Madison, Wisconsin 53706, U.S.A.
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Covariance between direct and maternal genetic effects on body weight in random-bred ICR mice at 2 through 10 weeks of age was estimated from cross-fostering experiments. The covariance contributes only a few percent of phenotypic variance at 2 weeks, but increases to 10–15% at later ages. Nearly all estimates are positive. We suggest that genes active during later parts of growth affect maternal performance more than those active during early growth, causing increased covariance at later ages. A model of combined genetic and persistent environmental effects on maternal performance is presented. Persistent effects of genetic or environmental variation in recent ancestors can influence covariance between relatives and response to selection.

Type
Research Article
Information
Genetics Research , Volume 45 , Issue 3 , June 1985 , pp. 287 - 297
Copyright
Copyright © Cambridge University Press 1985

References

REFERENCES

Ahlschwede, W. T. & Robison, O. W. (1971). Prenatal and postnatal influences on growth and backfat in swine. Journal of Animal Science 32, 10–16.CrossRefGoogle Scholar
Burfening, P. J., Kress, D. D. & Friedrich, R. L. (1981). Calving ease and growth rate of simmental-sired calves. III. Direct and maternal effects. Journal of Animal Science 53, 1210–1216.CrossRefGoogle ScholarPubMed
Cheverud, J. M. (1984). Evolution by kin selection: a quantitative genetic model illustrated by maternal performance in mice. Evolution 38, 766–777.CrossRefGoogle ScholarPubMed
Dickerson, G. E. (1947). Composition of hog carcasses as influenced by heritable differences in rate and economy of gain. Iowa Agricultural Experiment Station, Research Bulletin 354, pp. 489–524. Ames, Iowa.Google Scholar
Eisen, E. J. (1970). Maternal effects on litter size in mice. Canadian Journal of Genetics and Cytology 12, 209–216.CrossRefGoogle Scholar
Eisen, E. J. (1975). Results of growth curve analysis in rats and mice. Journal of Animal Science 42, 1008–1023.CrossRefGoogle Scholar
Eisen, E. J. & Durrant, B. S. (1980). Genetic and maternal environmental factors influencing litter size and reproductive efficiency in mice. Journal of Animal Science 50, 428–441.CrossRefGoogle ScholarPubMed
Eisen, E. J., Legates, J. E. & Robison, O. W. (1970). Selection for 12-day litter weight in mice. Genetics 64, 511–532.CrossRefGoogle ScholarPubMed
Falconer, D. S. (1965). Maternal effects and selection response. In Genetics Today, vol. 3, Proceedings of the Eleventh International Congress of Genetics (ed. Geerts, S. J.), pp. 763–774. Oxford: Pergamon Press.Google Scholar
Falconer, D. S. (1981). Introduction to Quantitative Genetics, 2nd ed.New York: Longman.Google Scholar
Hanrahan, J. P. (1976). Maternal effects and selection response with an application to sheep data. Animal Production 22, 359–369.Google Scholar
Hanrahan, J. P. & Eisen, E. J. (1973). Sexual dimorphism and direct and maternal genetic effects on body weight in mice. Theoretical and Applied Genetics 43, 39–45.CrossRefGoogle ScholarPubMed
Hanrahan, J. P. & Eisen, E. J. (1974). Genetic variation in litter size and 12-day weight in mice and their relationship with post-weaning growth. Animal Production 19, 13–23.Google Scholar
Hohenboken, W. D. & Brinks, J. S. (1971). Relationships between direct and maternal effects on growth in herefords. II. Partitioning of covariance between relatives. Journal of Animal Science 32, 26–34.CrossRefGoogle Scholar
Kuhlers, D. L., Chapman, A. B. & First, N. L. (1977). Estimates of maternal and grand maternal influences on weights and gains of pigs. Journal of Animal Science 44, 181–188.CrossRefGoogle Scholar
Li, C. C. (1975). Path Analysis - a primer. Pacific Grove, California: Boxwood Press.Google Scholar
Nagai, J., Eisen, E. J., Emsley, J. A. B. & McAllister, A. J. (1978). Selection for nursing ability and adult weight in mice. Genetics 88, 761–780.CrossRefGoogle ScholarPubMed
Riska, B., Atchley, W. R. & Rutledge, J. J. (1984). A genetic analysis of targeted growth in mice. Genetics 107, 79–101.CrossRefGoogle ScholarPubMed
Rutledge, J. J., Robison, O. W., Eisen, E. J. & Legates, J. E. (1972). Dynamics of genetic and maternal effects in mice. Journal of Animal Science 35, 911–918.CrossRefGoogle ScholarPubMed
Sas Institute, Inc. (1982). SAS User's Guide: Basics, 1982 ed. Cary, , North Carolina: SAS Institute, Inc.Google Scholar
Sokal, R. R. & Rohlf, F. J. (1981). Biometry. The Principles and Practice of Statistics in Biological Research, 2nd ed.San Francisco: Freeman.Google Scholar
Vesely, J. A. & Robison, O. W. (1971). Genetic and maternal effects on preweaning growth and type score in beef calves. Journal of Animal Science 32, 825–831.CrossRefGoogle ScholarPubMed
Willham, R. L. (1963). The covariance between relatives for characters composed of components contributed by related individuals. Biometrics 19, 18–27.CrossRefGoogle Scholar
Willham, R. L. (1972). The role of maternal effects in animal breeding: III. Biometrical aspects of maternal effects in animals. Journal of Animal Science 35, 1288–1293.CrossRefGoogle Scholar
Wright, S. (1968). Evolution and the Genetics of Populations, vol. 1: Genetic and Biometric Foundations. Chicago: University of Chicago Press.Google Scholar