Genetical Research

Research Article

Parental influences on X chromosome expression

Lesley M. Forrestera1 and J. D. Ansella1

a1 Dept of Zoology, University of Edinburgh, West Mains Rd, Edinburgh, EH9 3JT


Using mice that were mosaics for both Xce and phosphoglycerate kinase (Pgk-1) alleles, we have established that the parental source of the Xce gene may affect the probability with which the X chromosome carrying it will remain active. This effect was seen in one allelic combination of Xce but not in another. The relationship between these effects and other phenomena of maternal ‘imprinting’ is discussed.

(Received June 04 1984)

(Revised October 01 1984)