Genetical Research

Short Paper

Postmeiotic segregation as a source of mosaics in diploid organisms

John F. Lesliea1 p1 and Ward B. Watta1

a1 Department of Biological Sciences, Stanford University, Stanford, California 94305-2493, U.S.A.


Postmeiotic segregation (PMS) of genetic variants occurs when a DNA heteroduplex formed during meiotic recombination goes undetected by repair enzymes and is transmitted unresolved to the meiotic products. PMS provides an alternative explanation for the origin of mosaics now attributed to half-chromatid mutation. In multicellular diploid eukaryotes, PMS could result in mosaic individuals with unusual migration patterns for proteins studied by gel electrophoresis. If the gonade were mosaic, complex progenies containing as many as six phenotypic classes at a single locus could be produced.

(Received May 09 1984)


p1 Present address: Department of Plant Pathology, Throckmorton Hall, Kansas State University, Manhattan, Kansas 66506, U.S.A.