Behavioral and Brain Sciences

Short Communication

No blind schizophrenics: Are NMDA-receptor dynamics involved?

Glenn S. Sanders a1, Steven M. Platek a2 and Gordon G. Gallup Jr. a1

a1 Department of Psychology, State University of New York at Albany, Albany, NY 12222
a2 Department of Psychology, Drexel University, Philadelphia, PA 19102


Numerous searches have failed to identify a single co-occurrence of total blindness and schizophrenia. Evidence that blindness causes loss of certain NMDA-receptor functions is balanced by reports of compensatory gains. Connections between visual and anterior cingulate NMDA-receptor systems may help to explain how blindness could protect against schizophrenia.