a1 Department of Parasitology, Akita University School of Medicine, Hondo, Akita 010, Japan
a2 Department of Parasitology, Miyazaki Medical College, Kiyotake, Miyazaki 889-16, Japan
Excretory and secretory (ES) products collected from adult worms of Strongyloides ratti stimulated interleukin-3 (IL-3) production with mesenteric lymph node cells from infected C57BL/6 mice, hut not with normal mesenteric lymph node cells. The IL-3 stimulating components were not major IgG binding antigens. Activity of the IL-3 stimulating components was stable by treatment with protease, although reduced by heating in boiling water.
(Accepted November 27 1991)