The fetal origins of adult disease

Volume 6
Issue 02 - May 1994
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<div style="background: #FFFFFF; margin: 10px 10px 10px 10px; padding: 10px 10px 10px 20px; text-align: left; border-top: 1px dashed #a5bbd1; border-left: 10px solid #a5bbd1; font-family: Verdana, Geneva, sans-serif;"><br> <div style="font-size: 12px; padding: 0px 0px 10px 0px; font-weight:bold; color: #003366;">The fetal origins of adult disease</div><br><div style="font-size: 10px;"><b>DJP Barker (1994).</b><br /> <a href="http://journals.cambridge.org/action/displayJournal?jid=FMR">Fetal and Maternal Medicine Review</a>, <a href="http://journals.cambridge.org/action/displayJournal?jid=FMR&volumeId=6&bVolume=y#loc6 ">Volume 6</a>, <a href="http://journals.cambridge.org/action/displayIssue?jid=FMR&volumeId=6&issueId=02&iid=1375352"> Issue 02</a>, May 1994 pp 71-80 <br/> <a href="http://journals.cambridge.org/action/displayAbstract?aid=1375352">http://journals.cambridge.org/action/displayAbstract?aid=1375352</a></div></div>
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The fetal origins of adult disease

DJP Barker (1994).
Fetal and Maternal Medicine Review, Volume 6, Issue 02, May 1994 pp 71-80 http://journals.cambridge.org/action/displayAbstract?aid=1375352

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Fetal and Maternal Medicine Review (1994), 6 : 71-80 Cambridge University Press

doi:10.1017/S0965539500001005 (About doi)

Published online by Cambridge University Press 10 Oct 2008

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Fetal and Maternal Medicine Review (1994), 6:71-80 Cambridge University Press

doi:10.1017/S0965539500001005

Articles

The fetal origins of adult disease

DJP Barker^a1 ^c1

^a1MRC Environmental Epidemiology Unit, Southampton.

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barker d

Recent studies have shown that babies who are small for dates at birth, or who fail to grow in infancy, have, in adult life, raised blood pressure, impaired glucose tolerance, abnormal serum lipids, raised fibrinogen and high death rates from coronary disease, stroke and obstructive lung disease. This has led to the hypothesis that these diseases are ‘programmed’ in utero in response to an adverse environment.

Correspondence:

^c1 Professor DJP Barker MD, PhD, FRCP, FRCOG, Director, MRC Environmental Epidemiology Unit, Southampton General Hospital, Southampton SO9 4XY, UK.

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