Journal of Biosocial Science

Research Article

Family study in sickle Cell disease in Nigeria

F. E. A. Lesia1 and Ekpo E. E. Basseya1

a1 Lagos University Teaching Hospital, P. M. B. 12003, Lagos, Nigeria

A pilot survey has been made of Nigerian families at risk of producing SS haemoglobin homozygotes. Genotypes of parents and off-spring were investigated in twenty-five families. There is a suggestion that more SS children are produced where the first born suffers from haemoglobin SS disease. Mortality among offspring was higher in the study population than in the general population.

(Received January 05 1972)