Psychological Medicine

Original Article

Prognostic indices with brief and standard CBT for panic disorder: II. Moderators of outcome

MICHAEL G. T. DOWa1 c1, JUSTIN A. KENARDYa2, DEREK W. JOHNSTONa3, MICHELLE G. NEWMANa4, C. BARR TAYLORa5 and AILEEN THOMSONa6

a1 NHS Fife, Department of Clinical Psychology, Stratheden Hospital, Cupar, Fife, UK

a2 Centre for National Research on Disability and Rehabilitation Medicine, and School of Psychology, University of Queensland, Brisbane, Queensland, Australia

a3 Department of Psychology, Kings College, University of Aberdeen, UK

a4 Department of Psychology, Pennsylvania State University, PA, USA

a5 Department of Psychiatry and Behavioral Science, Stanford University School of Medicine, Stanford, CA, USA

a6 Health Psychology Department, Gloucestershire Royal Hospital, Gloucester, UK

ABSTRACT

Background Despite the growth of reduced therapist-contact cognitive behavioural therapy (CBT) programmes, there have been few systematic attempts to determine prescriptive indicators for such programmes vis-à-vis more standard forms of CBT delivery. The present study aimed to address this in relation to brief (6-week) and standard (12-week) therapist-directed CBT for panic disorder (PD) with and without agoraphobia. Higher baseline levels of severity and associated disability/co-morbidity were hypothesized to moderate treatment effects, in favour of the 12-week programme.

Method Analyses were based on outcome data from two out of three treatment groups (n=72) from a recent trial of three forms of CBT delivery for PD. The dependent variables were a continuous composite panic/anxiety score and a measure of clinical significance. Treatment×predictor interactions were examined using multiple and logistic regression analyses.

Results As hypothesized, higher baseline severity, disability or co-morbidity as indexed by strength of dysfunctional agoraphobic cognitions; duration of current episode of PD; self-ratings of panic severity; and the 36-item Short Form Health Survey (SF-36) (Mental component) score were all found to predict poorer outcome with brief CBT. A similar trend was apparent in relation to baseline level of depression. With high and low end-state functioning as the outcome measure, however, only the treatment×agoraphobic cognitions interaction was found to be significant.

Conclusions While there was no evidence that the above variables necessarily contraindicate the use of brief CBT, they were nevertheless associated with greater overall levels of post-treatment improvement with the 12-week approach.

(Online publication May 10 2007)

Correspondence

c1 Address for correspondence: Dr Michael G. T. Dow, Department of Psychology, University of Stirling, Stirling FK9 4LA, UK. (Email: mgtd1@stir.ac.uk)

Metrics
Related Content