a1 Department of Obstetrics and Gynecology, University of Colorado Health Science Center, Denver, Colorado, USA
Premature rupture of the membranes (PROM) and preterm birth
Preterm birth remains a paramount problem in health care worldwide. In the USA, approximately 6–10% of births occur preterm.1–3 Gestational age at birth is the most important determinant of an infant's morbidity and mortality. Preterm infants account for approximately 75% of neonatal deaths,3–5 as well as incalculable direct and indirect financial costs and morbidity.6–9
Correspondence:
c1 Kyung Seo, Department of Obstetrics and Gynecology, University of Colorado Health Science Center, Denver, Colorado, USA.