Epidemiology and Infection

Research Article

Outbreak with multi-resistant Salmonella Typhimurium DT104 linked to carpaccio, Denmark, 2005

S. ETHELBERGa1a2 c1, G. SØRENSENa3, B. KRISTENSENa4, K. CHRISTENSENa5, L. KRUSELLa5, A. HEMPEL-JØRGENSENa6, A. PERGEa7 and E. M. NIELSENa1

a1 Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, Copenhagen, Denmark

a2 Department of Epidemiology, Statens Serum Institut, Copenhagen, Denmark

a3 Danish Institute for Food and Veterinary Research, Copenhagen, Denmark

a4 Department of Clinical Microbiology, Skejby Hospital, Århus, Denmark

a5 Regional Veterinary and Food Control Authority, Århus County, Århus, Denmark

a6 Regional Medical Health Office, Midtyjlland, National Board of Health, Århus, Denmark

a7 Danish Veterinary and Food Administration, Copenhagen, Denmark

SUMMARY

We report an outbreak with Salmonella Typhimurium DT104 resistant to six different antibiotic classes. The outbreak occurred in Denmark in July/August 2005 and was traced to a single restaurant. In addition to patient interviews, an important tool in the investigation of this outbreak was comparison by multi-locus variable number of tandem repeat analysis (MLVA) typing of patient strains with strains from the food surveillance system. This showed that the source of the outbreak was imported beef served as carpaccio. Carpaccio, thinly sliced raw fillet of beef, has not previously been associated with outbreaks, but should be considered a high-risk food item. This outbreak was one of two in different European Union (EU) countries traced back to beef from one company in a third EU country. This underscores the importance of efficient international Salmonella surveillance and food-safety control systems enabling timely interventions within the EU.

(Accepted January 03 2007)

(Online publication March 05 2007)

Correspondence:

c1 Author for correspondence: Dr S. Ethelberg, Department of Bacteriology, Mycology and Parasitology, Statens Serum Institut, Artillerivej 5, DK-2300 Copenhagen S., Denmark. (Email: set@ssi.dk)

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