Thalamus & Related Systems



Interaction between neocortical and hippocampal networks via slow oscillations


Anton Sirota a1 and György Buzsáki a1c1
a1 Center for Molecular and Behavioral Neuroscience Rutgers, The State University of New Jersey, 197 University Avenue, Newark, USA

Article author query
sirota a   [Google Scholar] 
buzsáki g   [Google Scholar] 
 

Abstract

Both the thalamocortical and limbic systems generate a variety of brain state-dependent rhythms but the relationship between the oscillatory families is not well understood. Transfer of information across structures can be controlled by oscillations. We suggest that slow oscillation of the neocortex, which was discovered by Mircea Steriade, temporally coordinates the self-organized oscillations in the neocortex, entorhinal cortex, subiculum and hippocampus. Transient coupling between rhythms can guide bidirectional information transfer among these structures and might serve to consolidate memory traces.


Key Words: Gamma oscillations; ripples; membrane potential; memory; current-source density; entorhinal cortex; subiculum.

Correspondence:
c1 Correspondence should be addressed to: G. Buzsáki Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, 197 University Avenue, Newark, NJ 07102 New Jersey, USA tel: +1 973 353 1080 ext. 3131 fax: +1 973 353 1280 email: buzsáki@axon.rutgers.edu