Hostname: page-component-8448b6f56d-t5pn6 Total loading time: 0 Render date: 2024-04-23T12:41:51.295Z Has data issue: false hasContentIssue false

Cinnarizine—a labyrinthine sedative

Published online by Cambridge University Press:  29 June 2007

G. Towse
Affiliation:
Janssen Pharmaceutical Ltd., Janssen House, Chapel Street, Marlow, Bucks.

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Research Article
Copyright
Copyright © JLO (1984) Limited 1980

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Albernaz, P. L. M., Ganança, M. M., and Menon, A. D. (1968) The treatment of problems of hearing and equilibrium with cinnarizine. O. Hospital, 75, 941.Google Scholar
Albernaz, P. L. M., Ganança, M. M., Novo, N. F., and De Paiva, E. R. (1978) Flunarizine and cinnarizine as vestibular depressants. Oto-rhino-laryngology (ORL), 40, 92.Google Scholar
Amery, W. K., and Oosterveld, W. J. (1975) An evaluation of cinnarizine in aged patients with vertiginous complaints—a multicentre trial. Acta Therapeutica, 1, 39.Google Scholar
Cobb, S., Coen, L. W., Gitomer, S. L., and Iles, R. (1976) Effect of cinnarizine on nystagmus induced by rotation deceleration. Eye, Ear, Nose and Throat Monthly, (Jan).Google Scholar
Cott, E., and Davidovitch, S. (1976) Treatment with Stugeron in vertebro-basilar insufficiency (Unpublished report).Google Scholar
Deane, F. R., Wood, C. D., and Graybiel, A. (1967) Effect of drugs in altering susceptibility to motion sickness in aerobatics and the slow rotating room. Aerospace Medicine, 38, 842.Google Scholar
De Witt, G. (1963) Seasickness. A labyrinthological study. Acta Otolaryngologica (Supplement 108), 7.Google Scholar
Di Perri, T., Forconi, S., Guerrini, M., Pasini, F. L., Del Cipollar, R., Rossi, C., and Agnusdei, D. (1977) Action of cinnarizine on hyperviscosity of blood in patients with Peripheral obliterative arterial disease. Proceedings of the Royal Society of Medicine (Supplement 8), 70, 25.CrossRefGoogle ScholarPubMed
Emanuel, M. B. (1979) Specific calcium antagonists in the treatment of peripheral vascular disease. Angiology, 30 (7), 454.CrossRefGoogle ScholarPubMed
Gabriel, A., Wood, C. D., Miller, E. F. H., and Chamer, D. B. (1968) Diagnostic criteria for grading the severity of acute motion sickness. Aerospace Medicine, 39, 453.Google Scholar
Godfraind, T. (1968) Pharmacology of angiotensin antagonists In: Pharmacology of hormonal poly-peptides and proteins p. 47. (Eds. Black, N., Martin, L., and Paoletti, R.). Plenum Press. New York.Google Scholar
Godfraind, T., and Morel, N. (1977) An upper limit to the number of calcium ions in smooth muscle as estimated with cinnarizine. European Journal of Pharmacology, 41, 245.CrossRefGoogle Scholar
Heald, R. J., and Tristram, S. J. (1979) Seasickness, a success story. Chemist and Druggist (Supplement), March, 1979.Google Scholar
Pharmaceutica, Janssen (1971) Safety evaluation of cinnarizine treatment—an eight week double-blind study against placebo (Unpublished report).Google Scholar
Jongkees, L. B. W., and Philipszoon, A. J. (1960) Some nystagmographical methods for the investigation of the effects of drugs upon the labyrinth. Acta Physiologica et Pharmacologica (Netherlands), 9, 240.Google ScholarPubMed
Owens, F. D. (1974) An assessment of the efficacy and safety of cinnarizine in the treatment of vertiginous disease (Unpublished report).Google Scholar
Philipszoon, A. J. (1962) Influence of cinnarizine on the labyrinth and on vertigo. Clinical Pharmacology and Therapeutics, 3(2), 184.CrossRefGoogle ScholarPubMed
Reuter, C. A., and Emanuel, M. B. (1979) Specific calcium antagonists in the treatment of peripheral vascular disease. Coeur et Median (in press).Google Scholar
Richards, A. B., Hughes, F. N., and Forney, R. B. (1963) Evaluation of anti-motion sickness drugs by component measurement of nystagmus in guinea pigs. Current Therapeutic Research, 5(11), 587.Google ScholarPubMed
Schaper, W. K. A., Jageneau, A. H. M., and Xhonneux, R. (1963) Cinnarizine (R516), a specific angiotensin blocking coronary vasodilator. Life Science, 2, 963.CrossRefGoogle Scholar
Trumbull, R., Chinn, H. I., Maag, C. H., Milch, L. J., Handford, S. W., Seibert, R., Sperling, P., and Smith, P. K. (1960) Effect of certain drugs on the incidence of seasickness. Clinical Pharmacology and Therapeutics, 1, 280.CrossRefGoogle ScholarPubMed
Van Neuten, J. M., and Janssen, P. A. J. (1972) The effect of cinnarizine on peripheral circulation in dogs. European Journal of Pharmacology, 17, 103.CrossRefGoogle Scholar
Van Neuten, J. M., and Janssen, P. A. J. (1973) Comparative study of the effects of flunarizine and cinnarizine on smooth muscles and cardiac tissue. Archives Internationales de Pharmacodynamie et de Therapie, 204, 37.Google Scholar
Wood, C. D., and Graybiel, A. (1968) Evaluation of sixteen anti-motion sickness drugs under controlled laboratory conditions. Aerospace Medicine, 39, 1341.Google ScholarPubMed