The Journal of Laryngology & Otology

View from Beneath: Pathology in Focus

Malignant mesenchymoma of the larynx

Osamu Kawashimaa1 c1, Tamio Kameia1, Yuji Shimizua1, Takao Shizukaa1 and Morito Nakayamaa2

a1 Department of Otolaryngology, Gumma University School of Medicine, 3-39-15 Showa-machi, Maebashi-shi, Gumma 371

a2 Department of Internal Medicine, Yokosula Kyosai Hospital, 1-16 Yone gahamadori, Yokosuka-shi, Kangawa 238, Japan.


A Case report of a laryngeal malignant mesenchymoma, a very rare head and neck and even rarer laryngeal leison, is reported.

In this case, an 85-years-old man, who had undergone several panendoscopies and biopsies that were non-diagnostic, subsequently succumbed to pulmonary metastases and died from respiratory failure. At autospy, tumour cells were demonstrated to constiute both bone and straited muscle cell types. As the tumour cells differentiated into two types of specialized cells from one type of embryonal tissue, the diagnosis of maligant mesenchymoma was established.


c1 Dr Osamu Kawashima, Department of Otolaryngology, Gurma University School of Medicine, 3-39-15 Shawa-machi, Macbashi-shi, Gurma, Japan.