The Journal of Laryngology & Otology

Table of Contents - August 1994 - Volume 108, Issue 08  

Main Articles

Serum leucine aminopeptidase in head and neck cancer

L. N. Garga1, S. P. S. Yadava1 and Harbans Lala2 c1

a1 Departments of Otolaryngology, Medical College and Hospital, Rohtak-124001, India

a2 Departments of Biochemistry, Medical College and Hospital, Rohtak-124001, India

Abstract

Serum leucine aminopeptidase (LAP) activity was assayed in patients with head and neck cancer. The levels were found to be significantly higher than the controls. However, the rise in serum LAP was nearly the same in all the patients studied, irrespective of the character or histopathology of the lesion but varied with respect to the site involved, i.e. from about 40 per cent in cancer of the hypopharynx to more than 100 per cent in cancer of the nasopharynx. Serum LAP activity was found to increase with the extent of the lymph node spread. After treatment the levels were found to be reduced.

(Accepted April 09 1994)

Key words

Correspondence:

c1 Dr Harbans Lal, Associate Professor Biochemistry, 15/8FM, Medical College, Rohtak-124001, India..

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