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Cognitive sequelae in acute respiratory distress syndrome patients with and without recall of the intensive care unit

Published online by Cambridge University Press:  18 May 2007

MICHAEL J. LARSON ,
LINDELL K. WEAVER  and
RAMONA O. HOPKINS
MICHAEL J. LARSON
Affiliation:
Psychology Department, Brigham Young University, Provo, Utah Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida
LINDELL K. WEAVER
Affiliation:
Department of Medicine, Pulmonary and Critical Care Divisions, LDS Hospital, Salt Lake City, Utah University of Utah School of Medicine, Salt Lake City, Utah
RAMONA O. HOPKINS
Affiliation:
Psychology Department, Brigham Young University, Provo, Utah Department of Medicine, Pulmonary and Critical Care Divisions, LDS Hospital, Salt Lake City, Utah Neuroscience Center, Brigham Young University, Provo, Utah
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Abstract

Some critically ill patients have dramatic recollections of the intensive care unit (ICU), whereas 23–50% have little or no recollection of their ICU stay. In addition, cognitive impairments are common following critical illness and ICU treatment. Little is known regarding the relationship between cognitive sequelae and ICU recall. We assessed recall of the ICU and its relationship to cognitive functioning at hospital discharge and 1 and 2 years after discharge in 70 consecutive acute respiratory distress syndrome (ARDS) patients. Seventeen patients (24%) had no recall of the ICU. Patients without ICU recall had increased rates of cognitive sequelae at hospital discharge and 1-year follow-up compared with the ICU recall group. Patients without ICU recall had a greater magnitude of cognitive impairments at hospital discharge, but not at 1- or 2-year follow-up. Profile analysis showed significant group differences in general intellectual functioning, executive function, processing speed, and spatial skills at hospital discharge, but not at 1- or 2-year follow-up. Estimated premorbid intelligence scores were inversely related to the magnitude of cognitive sequelae, suggesting greater “cognitive reserve” in patients with fewer cognitive decrements. (JINS, 2007, 13, 595–605.)

Keywords

ARDSIntensive care unit (ICU)Cognitive outcomeCognitive reserveCriticalIllnessSequelaeMemory
Type
Research Article
Information
Journal of the International Neuropsychological Society , Volume 13 , Issue 4 , July 2007 , pp. 595 - 605
Copyright
© 2007 The International Neuropsychological Society

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