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Guideline-Concordant Versus Discordant Antimicrobial Therapy in Patients With Community-Onset Complicated Intra-abdominal Infections

Published online by Cambridge University Press:  29 March 2016

Lori L. Huang ,
Trevor C. Van Schooneveld ,
Robert D. Huang ,
Keith M. Olsen ,
Mark E. Rupp  and
Alan E. Gross
Lori L. Huang
Affiliation:
Veterans’ Affairs Medical Center, Patient Care Services, Ann Arbor, Michigan University of Nebraska Medical Center, College of Pharmacy, Omaha, Nebraska
Trevor C. Van Schooneveld
Affiliation:
University of Nebraska Medical Center, College of Medicine, Omaha, Nebraska Nebraska Medicine, Department of Infection Control and Epidemiology, Omaha, Nebraska
Robert D. Huang
Affiliation:
University of Nebraska Medical Center, College of Medicine, Omaha, Nebraska University of Michigan, Emergency Medicine, Ann Arbor, Michigan
Keith M. Olsen
Affiliation:
University of Nebraska Medical Center, College of Pharmacy, Omaha, Nebraska
Mark E. Rupp
Affiliation:
University of Nebraska Medical Center, College of Medicine, Omaha, Nebraska Nebraska Medicine, Department of Infection Control and Epidemiology, Omaha, Nebraska
Alan E. Gross*
Affiliation:
University of Nebraska Medical Center, College of Pharmacy, Omaha, Nebraska University of Nebraska Medical Center, College of Medicine, Omaha, Nebraska University of Illinois at Chicago College of Pharmacy, Department of Pharmacy Practice, Chicago, Illinois University of Illinois Hospital and Health Sciences System, Chicago, Illinois.
*
Address correspondence to Alan E. Gross, 833 South Wood Street, 164 PHARM, Chicago, IL 60612 (aegross@uic.edu).
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Abstract

Overall IDSA/SIS intra-abdominal infection guideline compliance was not associated with improved outcomes; however, there was a longer time to active therapy (P=.024) and higher mortality (P=.077) if empiric therapy was too narrow per guidelines. These findings support the need for the implementation of customized institutional guidelines adapted from the IDSA/SIS guidelines.

Infect Control Hosp Epidemiol 2016;37:855–858

Type
Concise Communications
Information
Infection Control & Hospital Epidemiology , Volume 37 , Issue 7 , July 2016 , pp. 855 - 858
Copyright
© 2016 by The Society for Healthcare Epidemiology of America. All rights reserved 

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Footnotes

PREVIOUS PRESENTATION. This study was presented in part as a poster (#1939) at the Interscience Conference on Antimicrobial Agents and Chemotherapy in Denver, Colorado, on September 13, 2013.

References

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