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Nanoparticle-based Calcium Phosphate Substrates: Gas Phase Synthesis and Potential Applications

Published online by Cambridge University Press:  31 January 2011

Renato Camata ,
Rebbeca Kraft ,
Marco Bottino  and
Parimal V Bapat
Renato Camata
Affiliation:
camata@uab.edu, University of Alabama at Birmingham, Physics, Birmingham, Alabama, United States
Rebbeca Kraft
Affiliation:
KRAFTRE1@GCC.EDU, University of Alabama at Birmingham, Physics, Birmingham, Alabama, United States
Marco Bottino
Affiliation:
bottino@uab.edu, University of Alabama at Birmingham, Materials Science and Engineering, Birmingham, Alabama, United States
Parimal V Bapat
Affiliation:
parimal3@uab.edu, University of Alabama at Birmingham, Physics, Birmingham, Alabama, United States
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Abstract

Emulating the ECM microenvironment of natural tissue and understanding how such an environment affects integrin function is a major goal of regenerative medicine and tissue engineering. In this work we have combined laser and aerosol techniques to create nanoengineered substrates comprising calcium phosphate nanoparticles of well controlled size on atomically flat SiO2 layers. In our process, gas suspended calcium phosphate nanoparticles are generated by ablation of solid a hydroxyapatite target inside a tube furnace at 800-900°C in presence of Argon/H2O flow using a KrF excimer laser and deposited on a silicon substrate via electrostatic precipitation.

Keywords

ablationadhesivecrystalline
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1236: Symposium SS – Biosurfaces and Biointerfaces , 2009 , 1236-SS08-51
Copyright
Copyright © Materials Research Society 2010

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