Epidemiology and Infection

Short Report

Trypanosoma

Trypanosoma cruzi screening in Texas blood donors, 2008–2012

M. N. GARCIAa1 c1, L. WOC-COLBURNa1, S. N. ROSSMANNa2, R. L. TOWNSENDa3, S. L. STRAMERa3, M. BRAVOa4, H. KAMELa4, R. BEDDARDa5, M. TOWNSENDa6, R. OLDHAMa6, M. E. BOTTAZZIa1, P. J. HOTEZa1 and K. O. MURRAYa1 c1

a1 Section of Pediatric Tropical Medicine, Department of Pediatrics, National School of Tropical Medicine, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA

a2 Gulf Coast Regional Blood Center, Houston, TX, USA

a3 American Red Cross, Gaithersburg, MD, USA

a4 Blood Systems Incorporated, Scottsdale, AZ, USA

a5 South Texas Blood & Tissue Center, San Antonio, TX, USA

a6 Coffee Memorial Blood Center, Amarillo, TX, USA

SUMMARY

Chagas disease is an important emerging disease in Texas that results in cardiomyopathy in about 30% of those infected with the parasite Trypanosoma cruzi. Between the years 2008 and 2012, about 1/6500 blood donors were T. cruzi antibody-confirmed positive. We found older persons and minority populations, particularly Hispanic, at highest risk for screening positive for T. cruzi antibodies during routine blood donation. Zip code analysis determined that T. cruzi is associated with poverty. Chagas disease has a significant disease burden and is a cause of substantial economic losses in Texas.

(Received March 07 2014)

(Revised July 28 2014)

(Accepted August 06 2014)

(Online publication August 29 2014)

Key words

  • Blood donors;
  • Chagas disease;
  • repeat reactive;
  • RIPA;
  • risk factors;
  • seroprevalence;
  • Trypanosoma cruzi

Correspondence

c1 Author for correspondence: Mrs M. N. Garcia, MPH, 1102 Bates Avenue #550, Houston, TX 77030, USA. (Email: mnolan@bcm.edu) [M.N.G] (Email: kmurray@bcm.edu) [K.O.M.]

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