Behavioral and Brain Sciences

Open Peer Commentary
Controversies in Neuroscience V: Persistent pain

Sex differences in pain do exist: The role of biological and psychosocial factors

Gary B. Rollman a1
a1 Department of Psychology, University of Western Ontario, London, Ontario N6A 5C2 Canada


The evidence favoring sex differences in pain seems compelling (berkley). This commentary considers the role of such factors as anxiety, somatosensory amplification, and coping style in accounting for the differential response to pain in the laboratory and clinic, and emphasizes the need to base evaluation and treatment upon individual reports rather than gender-based stereotypes.