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Silicon carbide quantum dots for bioimaging

Published online by Cambridge University Press:  28 September 2012

David Beke ,
Zsolt Szekrényes ,
Denes Pálfi ,
Gergely Róna ,
István Balogh ,
Pal Andor Maák ,
Gergely Katona ,
Zsolt Czigány ,
Katalin Kamarás  and
Balazs Rózsa
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David Beke*
Affiliation:
Institute for Solid State Physics and Optics, Wigner Research Centre for Physics, Hungarian Academy of Sciences, H-1121 Budapest, Hungary; and Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, H-1111 Budapest, Hungary
Zsolt Szekrényes
Affiliation:
Institute for Solid State Physics and Optics, Wigner Research Centre for Physics, Hungarian Academy of Sciences, H-1121 Budapest, Hungary
Denes Pálfi
Affiliation:
The Faculty of Information Technology, Pázmány Péter Catholic University, H-1083 Budapest, Hungary; and Institute of Experimental Medicine, Hungarian Academy of Sciences, H-1083 Budapest, Hungary
Gergely Róna
Affiliation:
Institute of Enzymology, Research Centre of Natural Sciences, Hungarian Academy of Sciences, H-1113 Budapest, Hungary
István Balogh
Affiliation:
Institute for Solid State Physics and Optics, Wigner Research Centre for Physics, Hungarian Academy of Sciences, H-1121 Budapest, Hungary
Pal Andor Maák
Affiliation:
Department of Atomic Physics, Budapest University of Technology and Economics, H-1111 Budapest, Hungary
Gergely Katona
Affiliation:
Institute of Experimental Medicine, Hungarian Academy of Sciences, H-1083 Budapest, Hungary
Zsolt Czigány
Affiliation:
Institute for Technical Physics and Materials Science, Research Centre of Natural Sciences, Hungarian Academy of Sciences, H-1121 Budapest, Hungary
Katalin Kamarás
Affiliation:
Institute for Solid State Physics and Optics, Wigner Research Centre for Physics, Hungarian Academy of Sciences, H-1121 Budapest, Hungary
Balazs Rózsa
Affiliation:
The Faculty of Information Technology, Pázmány Péter Catholic University, H-1083 Budapest, Hungary; and Institute of Experimental Medicine, Hungarian Academy of Sciences, H-1083 Budapest, Hungary
Laszlo Buday
Affiliation:
Institute of Enzymology, Research Centre of Natural Sciences, Hungarian Academy of Sciences, H-1113 Budapest, Hungary
Beata Vértessy
Affiliation:
Institute of Enzymology, Research Centre of Natural Sciences, Hungarian Academy of Sciences, H-1113 Budapest, Hungary
Adam Gali
Affiliation:
Institute for Solid State Physics and Optics, Wigner Research Centre for Physics, Hungarian Academy of Sciences, H-1121 Budapest, Hungary; and Department of Atomic Physics, Budapest University of Technology and Economics, H-1111 Budapest, Hungary
*
a)Address all correspondence to this author. e-mail: beke.david@wigner.mta.hu
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Abstract

Luminescent nanocrystals or quantum dots (QDs) have great potential for bioanalysis as well as optoelectronics. Here we report an effective and inexpensive fabrication method of silicon carbide quantum dots (SiC QDs), with diameter below 8 nm, based on electroless wet chemical etching. Our samples show strong violet-blue emission in the 410–450 nm region depending on the solvents used and particle size. The cytotoxic properties of the SiC QDs based on alamarBlueTM assay cells were studied. The presence of the QDs dots does not affect cell growth in a wide concentration range. Two-photon excitation showed significant response from SiC nanocrystals that were injected into hippocampal CA1 pyramidal cells.

Type
Articles
Information
Journal of Materials Research , Volume 28 , Issue 2: Focus Section: Silicon-based Nanoparticles for Biosensing and Biomedical Applications , 28 January 2013 , pp. 205 - 209
Copyright
Copyright © Materials Research Society 2012

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References

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