Behavioral and Brain Sciences

Open Peer Commentary
Quartz & Sejnowski: Cognitive development

Classical conditioning has much to do with LTP

Richard F. Thompson a1
a1 Neuroscience Program, University of Southern California, Los Angeles, CA 90089-2520


Shors & Matzel somewhat lightly dismiss the evidence that a process like LTP may underlie the learning-induced increase in neuronal activity in the hippocampus in eyeblink conditioning. I provide some 12 lines of evidence supporting this hypothesis and the further hypothesis that this learning-induced LTP-like hippocampal plasticity can play a critical role in certain aspects of learned behavior.