Behavioral and Brain Sciences

Short Communication

Beyond acetylcholine: Next steps for sleep and memory research

Jessica D. Payne a1, Willoughby B. Britton a1, Richard R. Bootzin a1 and Lynn Nadel a1
a1 Department of Psychology, University of Arizona, Tucson, AZ 85721


We consider Walker's thorough review in the context of thinking about future research on the relation between sleep and memory. We first address methodological issues including type of memory and sleep-stage dependency. We suggest a broader investigation of potential signaling molecules that may be critical to sleep-related consolidation. A brief review of the importance of the stress hormone cortisol illustrates this point.