Behavioral and Brain Sciences

Short Communication

Spatial integration in perception and cognition: An empirical approach to the pathophysiology of schizophrenia

Yue Chen a1

a1 Mailman Research Center, Harvard Medical School/McLean Hospital, Belmont, MA 02478


Evidence for a dysfunction in cognitive coordination in schizophrenia is emerging, but it is not specific enough to prove (or disprove) this long-standing hypothesis. Many aspects of the external world are spatially mapped in the brain. A comprehensive internal representation relies on integration of information across space. Focus on spatial integration in the perceptual and cognitive processes will generate empirical data that shed light on the pathophysiology of schizophrenia.