Behavioral and Brain Sciences

Open Peer Commentary
Quartz & Sejnowski: Cognitive development

Long term potentiation: Attending to levels of organization of learning and memory mechanisms

Matthew Shapiro a1 and Eric Hargreaves a1
a1 Department of Psychology, McGill University, Montreal, Quebec, Canada H3A 1B1


Shors & Matzel set up a straw man, that LTP is a memory storage mechanism, and knock him down without due consideration of the important relations among different levels of organization and analysis regarding LTP, learning, and memory. Assessing these relationships requires analysis and hypotheses linking specific brain regions, neural circuits, plasticity mechanisms, and task demands. The issue addressed by the authors is important, but their analysis is off target.