Behavioral and Brain Sciences

Open Peer Commentary
Gold & Stoljar: A neuron doctrine

Neuronal connectivity, regional differentiation, and brain damage in humans

Dahlia W. Zaidel a1
a1 Department of Psychology, University of California at Los Angeles, Los Angeles, CA 90095-1653


When circumscribed brain regions are damaged in humans, highly specific impairments in language, memory, problem solving, and cognition are observed. Neurosurgery such as “split brain” or hemispherectomy, for example, has shown that encompassing regions, the left and right cerebral hemispheres, each control human behavior in unique ways. Observations stretching over 100 years of patients with unilateral focal brain damage have revealed, without the theoretical benefits of “cognitive neuroscience” or “cognitive psychology,” that human behavior is indeed controlled by the brain and its neurons.