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Biocompatibility of Te–As–Se glass fibers for cell-based bio-optic infrared sensors

Published online by Cambridge University Press:  03 March 2011

Allison A. Wilhelm ,
Pierre Lucas ,
Diana L. DeRosa  and
Mark R. Riley
Allison A. Wilhelm
Affiliation:
Department of Material Science and Engineering, University of Arizona, Tucson, Arizona 85721
Pierre Lucas*
Affiliation:
Department of Material Science and Engineering, University of Arizona, Tucson, Arizona 85721
Diana L. DeRosa
Affiliation:
Department of Agricultural and Biosystems Engineering, University of Arizona, Tucson, Arizona 85721
Mark R. Riley
Affiliation:
Department of Agricultural and Biosystems Engineering, University of Arizona, Tucson, Arizona 85721
*
a) Address all correspondence to this author. e-mail: Pierre@u.arizona.edu
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Abstract

The chemical stability and toxicity of Te–As–Se (TAS) infrared fibers are investigated. These fibers are used for biosensing applications that involve direct contact with live cultivated human cells. It is shown that TAS fibers exhibit a small oxidation layer after extended exposure to air. This layer is highly soluble in water and easily removed. However, the TAS glass itself is stable in water over several days. While oxidized fibers release arsenate ions, which result in toxic effects to the cells, fresh or washed fibers show no toxic effects. A good correlation is shown between surface etching and the disappearance of toxicity.

Keywords

AsInfrared (IR) spectroscopySensor
Type
Articles
Information
Journal of Materials Research , Volume 22 , Issue 4 , April 2007 , pp. 1098 - 1104
Copyright
Copyright © Materials Research Society 2007

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