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British Journal of Nutrition (1998), 80 : S77-S112 Cambridge University Press
doi:10.1079/BJN19980106
Published online by Cambridge University Press 09 Mar 2007
 
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British Journal of Nutrition (1998), 80:S77-S112 Cambridge University Press
Copyright © The Nutrition Society 1998
doi:10.1079/BJN19980106

Research Article

Functional food science and defence against reactive oxidative species

A. T. Diplocka1 c1, J.-L. Charuleuxa2, G. Crozier-Willia3, F. J. Koka4, C. Rice-Evansa1, M. Roberfroida5, W. Stahla6 and J. Viña-Ribesa7

a1 International Antioxidant Research Centre, UMDS, Guy's Hospital, St Thomas Street, London SEl 9RT, UK
a2 F. Hoffmann-La Roche Ltd, Business Unit Carotenoids, Headofice Kaiseruugst VMl Building, CH04002 Basel, Switzerland
a3 Nestec Ltd, Nestlè Research Center, Vers-Chez-La-Blanc, PO Box 44, CH-1000 Lausanne 26, Switzerland
a4 Division of Human Nutrition and Epidemiology, Wageningen Agricultural University, PO Box 8129, NL 6700 EV, Wageningen, The Netherlands
a5 UCL, Ecole de Pharmacie, Tour Van Helmont, Avenue E. Mounier, B-1200 Brussels, Belgium
a6 Heinrich-Heine-University Dusseldorf, Medizinische Einrichtungen, Institut für Physiologische Chemie I, Postfach 10 10 07, 0-40001 Dusseldorf, Germany
a7 Universidad de Valencia, Fucultad de Medicina, Departamento de Fisiologia, Avenida Blasco Ibajez 17, E-46010 Valencia, Spain
Article author query
diplock at PubMed  Google Scholar
charuleux j- PubMed  Google Scholar
crozier-willi g PubMed  Google Scholar
kok fj PubMed  Google Scholar
rice-evans c PubMed  Google Scholar
roberfroid m PubMed  Google Scholar
stahl w PubMed  Google Scholar
viña-ribes j PubMed  Google Scholar

Abstract

This paper assesses critically the science base that underpins the argument that oxidative damage is a significant causative factor in the development of human diseases and that antioxidants are capable of preventing or ameliorating these disease processes. The assessment has been carried out under a number of headings, and some recommendations for future research are made based on the present day knowledge base.

Correspondence:

c1 *fax +44 (0) 171403 7195, +44(0) 171 955 4521.

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